Article

Image-based spatial transcriptomics identifies molecular niche dysregulation associated with distal lung remodeling in pulmonary fibrosis

2023-12-16

Abstract excerpt

The human lung is structurally complex, with a diversity of specialized epithelial, stromal and immune cells playing specific functional roles in anatomically distinct locations, and large-scale changes in the structure and cellular makeup of this distal lung is a hallmark of pulmonary fibrosis (PF) and other progressive chronic lung diseases. Single-cell transcriptomic studies have revealed numerous disease-emerg...

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Literature Corpus work: ee2818c2-4151-53b8-bd2a-bc9b2f78f623
DOI: 10.1101/2023.12.15.571954

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