Article

Early events marking lung fibroblast transition to profibrotic state in idiopathic pulmonary fibrosis

2022-08-02

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Idiopathic Pulmonary Fibrosis (IPF) is an age-associated progressive lung disease with accumulation of scar tissue impairing gas exchange. Previous high-throughput studies elucidated the role of cellular heterogeneity and molecular pathways in advanced disease. However, critical pathogenic pathways occurring in the transition of fibroblasts from normal to profibrotic have be...

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Literature Corpus work: 68ff3212-b4bb-5380-817b-aea40a07d627
DOI: 10.1101/2022.07.29.501956

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