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Article

Spatial Transcriptomic Characterization of Novel Pathologic Niches in IPF

2023-12-14

Abstract excerpt

<h4>ABSTRACT</h4> An unmet medical need persists in Idiopathic Pulmonary fibrosis (IPF), for which treatments additional to anti-fibrotic therapy are needed. Single cell RNA sequencing (scRNA-seq) has advanced our understanding of IPF with cell type-specific insights but lacks cellular tissue context. Spatial transcriptomics addresses this by providing spatially resolved gene expression, enabling gene and cell ty...

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Literature Corpus work
bbc03303-6699-5df3-9f51-217f58d03fc7
DOI
10.1101/2023.12.13.571464
Open publication

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