Article

A unique mechanism explaining the outstanding performance of a newly discovered doxycycline riboswitch

2025-11-19

Abstract excerpt

Synthetic riboswitches offer a versatile and protein-independent solution for conditional gene regulation. They consist of a regulatory domain and an aptamer domain that binds a specific ligand, with their performance largely depending on the ability of the aptamer to control the regulatory domain. Expanding the range of synthetic riboswitches therefore requires the discovery and characterization of new regulatory...

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Literature Corpus work: 49469914-6a36-5319-9847-7fcae501b025
DOI: 10.1101/2025.11.11.687352

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