Article

Electrophysiological characterisation of iPSC-derived human β-like cells and an <i>SLC30A8</i> disease model

2023-10-18

Abstract excerpt

iPSC-derived human β-like cells (BLC) hold promise for both therapy and disease modelling, but their generation remains challenging and their functional analyses beyond transcriptomic and morphological assessments remain limited. Here, we validate an approach using multicellular and single cell electrophysiological tools to evaluate BLCs functions. The Multi-Electrode Arrays (MEAs) measuring the extracellular elec...

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Literature Corpus work: e334c80b-b589-57ff-8a4f-ed296fa9e825
DOI: 10.1101/2023.10.17.561014

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