Article

High-purity stem cell-derived β-cells recapitulate key transcriptional and functional features of human islets

2026-05-26

Abstract excerpt

<h4>ABSTRACT</h4> Human pluripotent stem cell-derived islets (SC-islets) offer an excellent medium for human pancreatic disease modelling and mechanistic studies into diabetes. While substantial progress has been made in differentiation protocols, their implementation in different laboratories result in variable β-cell proportions with contaminant non-endocrine and proliferative cell types. To date, no facility-l...

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Literature Corpus work: 7c75235d-c236-50d0-9800-4251b7c00ff9
DOI: 10.64898/2026.05.22.726825

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