Article

Meiotic shugoshins differ from mitotic ones by arginine-reach C-terminal motif in yeast, plant, animals, and human

2016-08-06

Abstract excerpt

<h4>Background: </h4> Shugoshins (SGOs) are proteins that protect cohesins located at the centromeres of sister chromatids from their early cleavage during mitosis and meiosis in plants, fungi, and animals. Their function is to prevent premature sister-chromatid disjunction and segregation. Meiotic SGOs prevent segregation of sister chromatids in meiosis I, thus permitting homologous chromosomes to segregate and r...

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Literature Corpus work: e2910192-f062-526d-ba4e-9ee0d5744987
DOI: 10.7287/peerj.preprints.2342v1

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