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Article

Sisters unbound is required for meiotic centromeric cohesion in Drosophila melanogaster.

Genetics - 1 Nov 2014

Krishnan Badri, Thomas Sharon E, Yan Rihui, Yamada Hirotsugu, Zhulin Igor B, McKee Bruce D

Abstract excerpt

Regular meiotic chromosome segregation requires sister centromeres to mono-orient (orient to the same pole) during the first meiotic division (meiosis I) when homologous chromosomes segregate, and to bi-orient (orient to opposite poles) during the second meiotic division (meiosis II) when sister chromatids segregate. Both orientation patterns require cohesion between sister centromeres, which is established...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25194162
DOI: 10.1534/genetics.114.166009
PMCID: PMC4224182

Genes

SMC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Sisters unbound is required for meiotic centromeric cohesion in Drosophila melanogaster.PMID 25194162Read ↗

SOLO: a meiotic protein required for centromere cohesion, coorientation, and SMC1 localization in Drosophila melanogaster.Semantic proximity Read ↗

Centromeric cohesion is protected twice at meiosis, by SHUGOSHINs at anaphase I and by PATRONUS at interkinesis.Semantic proximity Read ↗

Identification of sisters separate (ssep), a gene required for meiotic centromere cohesion in Drosophila melanogaster.Semantic proximity Read ↗

INCENP and Aurora B promote meiotic sister chromatid cohesion through localization of the Shugoshin MEI-S332 in Drosophila.Semantic proximity Read ↗

Meiosis-specific cohesin component, Stag3 is essential for maintaining centromere chromatid cohesion, and required for DNA repair and synapsis between homologous chromosomes.Semantic proximity Read ↗

A REC8-dependent plant Shugoshin is required for maintenance of centromeric cohesion during meiosis and has no mitotic functions.Semantic proximity Read ↗

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