Article

Sema7A and Sema4D Heterodimerization is Essential for Membrane Targeting and Neocortical Wiring

2023-02-10

Abstract excerpt

<h4>SUMMARY</h4> Disruption of neocortical circuitry and architecture in humans causes numerous neurodevelopmental disorders. Neocortical cytoarchitecture is orchestrated by various transcription factors such as Satb2 that control target genes during strict time windows. In humans, mutations of SATB2 cause SATB2 Associated Syndrome (SAS), a multisymptomatic syndrome involving intellectual disability, speech delay...

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Literature Corpus work: e243ca3e-f6bf-58b8-8c99-50b0717061f1
DOI: 10.1101/2023.02.10.527998

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