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The effects of semaphorin 3A in bone and cartilage metabolism: fundamental mechanism and clinical potential

23 Nov 2023

Abstract excerpt

Semaphorin 3A (Sema3A) is a neuroinformatic protein molecule with widespread expression across various tissues and organs. Recent investigations have unveiled its pivotal role in the skeletal system, primarily through its binding interactions with two co-receptors, neuropilin-1 (Nrp-1) and members of the plexin family. Prior research has confirmed the expression of Sema3A and its receptors in both osteocytes and...

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PMID: 38078001
DOI: 10.3389/fcell.2023.1321151

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