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Article

Genes regulated by SATB2 during neurodevelopment contribute to schizophrenia and educational attainment.

PLoS genetics - 1 Jul 2018

Whitton Laura, Apostolova Galina, Rieder Dietmar, Dechant Georg, Rea Stephen, Donohoe Gary, Morris Derek W

Abstract excerpt

SATB2 is associated with schizophrenia and is an important transcription factor regulating neocortical organization and circuitry. Rare mutations in SATB2 cause a syndrome that includes developmental delay, and mouse studies identify an important role for SATB2 in learning and memory. Interacting partners BCL11B and GATAD2A are also schizophrenia risk genes indicating that other genes interacting with or are...

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Source

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Identifiers

PMID: 30040823
DOI: 10.1371/journal.pgen.1007515
PMCID: PMC6097700

Genes

SATB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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