Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Semaphorin heterodimerization in cis regulates membrane targeting and neocortical wiring.

Nature communications - 16 Aug 2024

Bessa Paraskevi, Newman Andrew G, Yan Kuo, Schaub Theres, Dannenberg Rike, Lajkó Denis, Eilenberger Julia, Brunet Theresa, Textoris-Taube Kathrin, Kemmler Emanuel, Deng Penghui, Banerjee Priyanka, Ravindran Ethiraj, Preissner Robert, Rosário Marta, Tarabykin Victor

Abstract excerpt

Disruption of neocortical circuitry and architecture in humans causes numerous neurodevelopmental disorders. Neocortical cytoarchitecture is orchestrated by various transcription factors such as Satb2 that control target genes during strict time windows. In humans, mutations of SATB2 cause SATB2 Associated Syndrome (SAS), a multisymptomatic syndrome involving epilepsy, intellectual disability, speech delay, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Axons
Share to Corpus Callosum

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epilepsy

Share to Glycosylation

Share to Matrix Attachment Region Binding Proteins

Share to Neocortex

Share to Protein Multimerization

Share to Semaphorins

Source

Open in PubMed Open full text

Identifiers

PMID: 39152101
DOI: 10.1038/s41467-024-51009-1
PMCID: PMC11329519

Genes

SATB2
GPI

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Semaphorin heterodimerization in cis regulates membrane targeting and neocortical wiring.PMID 39152101Read ↗

Sema7A and Sema4D Heterodimerization is Essential for Membrane Targeting and Neocortical WiringSemantic proximity Read ↗

Satb2 regulates callosal projection neuron identity in the developing cerebral cortex.Semantic proximity Read ↗

Mutual regulation between Satb2 and Fezf2 promotes subcerebral projection neuron identity in the developing cerebral cortex.Semantic proximity Read ↗

Glycosylphosphatidylinositol-Anchored Immunoglobulin Superfamily Cell Adhesion Molecules and Their Role in Neuronal Development and Synapse RegulationSemantic proximity Read ↗

A network of genetic repression and derepression specifies projection fates in the developing neocortex.Semantic proximity Read ↗

Cognitive function depends upon <i>Satb2</i> gene dosage in cortical projection neuronsSemantic proximity Read ↗

Abnormalities in pharyngeal arch-derived structures in SATB2-associated syndrome.Semantic proximity Read ↗

Gene deletion mutants reveal a role for semaphorin receptors of the plexin-B family in mechanisms underlying corticogenesis.Semantic proximity Read ↗

Upregulated SEMA3C in astrocytes contributes to Rett Syndrome phenotypesSemantic proximity Read ↗

Dscam2 suppresses synaptic strength through a PI3K-dependent endosomal pathway.Semantic proximity Read ↗

Bcl11a (Ctip1) Controls Migration of Cortical Projection Neurons through Regulation of Sema3c.Semantic proximity Read ↗

STAM2, a member of the endosome-associated complex ESCRT-0 is highly expressed in neuronsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.