Article

Non-Elastic Remodeling of the 3D Extracellular Matrix by Cell-Generated Forces

2017-09-27

Abstract excerpt

The mechanical properties of the extracellular matrix (ECM) – a complex, 3D, fibrillar scaffold of cells in physiological environments – modulate cell behavior and can drive tissue morphogenesis, regeneration, and disease progression. For simplicity, it is often convenient to assume these properties to be time-invariant. In living systems, however, cells dynamically remodel the ECM and create time-dependent local...

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Identifiers and source

Literature Corpus work: e223765f-8e33-5827-9236-1d47e2a7c9fa
DOI: 10.1101/193458

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