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Article

The extracellular matrix mechanics in the vasculature.

Nature cardiovascular research - 1 Aug 2023

Wang Dafu, Brady Travis, Santhanam Lakshmi, Gerecht Sharon

Abstract excerpt

Mechanical stimuli from the extracellular matrix (ECM) modulate vascular differentiation, morphogenesis and dysfunction of the vasculature. With innovation in measurements, we can better characterize vascular microenvironment mechanics in health and disease. Recent advances in material sciences and stem cell biology enable us to accurately recapitulate the complex and dynamic ECM mechanical microenvironment for...

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PMID: 39195965
DOI: 10.1038/s44161-023-00311-0

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