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Article

Endothelial cell traction and ECM density influence both capillary morphogenesis and maintenance in 3-D.

American journal of physiology. Cell physiology - 1 Jul 2009

Kniazeva Ekaterina, Putnam Andrew J

Abstract excerpt

Identifying the mechanisms regulating angiogenesis in pathological conditions such as cancer and heart disease is crucial to develop successful therapies. The dependence of angiogenesis on characteristic properties of these conditions, such as alterations in tissue stiffness due to changes in the composition of the extracellular matrix (ECM), may shed light on potential therapeutic strategies. Prior studies have...

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Identifiers

PMID: 19439531
DOI: 10.1152/ajpcell.00018.2009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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