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Proinflammatory and cytotoxic CD38<sup>+</sup>HLA-DR<sup>+</sup>effector memory CD8<sup>+</sup>T cells are peripherally expanded in human cardiac allograft vasculopathy

2024-12-26

Abstract excerpt

<h4>Background</h4> T cell mediated immunity is reported to play a pathogenic role in cardiac allograft vasculopathy (CAV) in heart transplant (HTx) patients. However, peripheral blood CD8 + T cells have not been previously characterized in CAV. This study aimed to identify potentially pathogenic circulating CD8 + T cell populations in high grade CAV patients using cellular indexing of transcriptomes and epitopes...

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Literature Corpus work
e1bce8a7-8dbb-57d2-ad51-2f377b7adc18
DOI
10.1101/2024.12.23.24319590
Open publication

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Proinflammatory and cytotoxic CD38<sup>+</sup>HLA-DR<sup>+</sup>effector memory CD8<sup>+</sup>T cells are peripherally expanded in human cardiac allograft vasculopathyDOI 10.1101/2024.12.23.24319590
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