Article

Single-cell RNA-seq reveals altered plasma cell subsets and decreased cytotoxicity of NK cells in patients with Kawasaki disease

2024-12-28

Abstract excerpt

Abstract Background:Kawasaki disease (KD) is a multisystemic vasculitis inflammatory syndrome that leads to coronary artery lesions (CALs). The pathogenesis and therapeutic strategies of KD are worth further exploring. Using single-cell RNA sequencing (scRNA-seq), our study aimed to explore the landscape of peripheral blood mononuclear cells (PBMCs) and B cell subsets in patients with KD, providing helpful evidenc...

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Literature Corpus work: 934e15df-7ca0-5a81-8355-a425e4c460a8
DOI: 10.22541/au.173535849.97810348/v1

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