Article

Single-cell RNA-seq reveals altered plasma cell subsets and decreased cytotoxicity of NK cells in patients with Kawasaki disease

2025-02-08

Abstract excerpt

<h4>Aim</h4> The pathogenesis and therapeutic strategies of Kawasaki disease (KD) are worth further exploring. Using single-cell RNA sequencing (scRNA-seq), our study aimed to explore the landscape of peripheral blood mononuclear cells (PBMCs) in patients with KD. <h4>Methods</h4> We analyzed the scRNA-seq data of three patients with KD and three healthy controls from the GSE168732 dataset. Additionally, we expl...

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Literature Corpus work: bc7aeeda-4477-5df3-bb03-97cb47aab60f
DOI: 10.1101/2025.02.03.636324

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