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Single-Cell Multi-Omics Identifies Specialized Cytotoxic and Migratory CD8 + Effector T Cells in Acute Myocarditis

5 Aug 2025

Abstract excerpt

BACKGROUND: Acute myocarditis (AM), particularly fulminant myocarditis (FM), is an infrequent but life-threatening cardiac inflammation, with limited effective precision-targeted treatments available. This urgent clinical challenge has prompted further investigations into the mechanisms underlying this pathology to develop novel therapeutic approaches. METHODS: We enrolled 40 patients diagnosed with AM (24 mild,...

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PMID: 40762079
DOI: 10.1161/circulationaha.125.073836

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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