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Multi-organ single-cell transcriptomics of immune cells uncovered organ-specific gene expression and functions

2023-05-31

Abstract excerpt

Despite the large number of publicly available single-cell datasets, there is a limited understanding of the distinct resident immune cells and their concomitant features in diverse human organs. To address this, we compiled a dataset of 114,275 CD45+ immune cells from 14 organs from healthy donors. Although the transcriptome of immune cells is constant across organs, organ-specific gene expression changes were d...

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Literature Corpus work
0e77af37-43cb-5462-986a-e45db87af6aa
DOI
10.1101/2023.05.29.542692
Open publication

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Multi-organ single-cell transcriptomics of immune cells uncovered organ-specific gene expression and functionsDOI 10.1101/2023.05.29.542692
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