Article

Spatial control of genome editing activity enables localized immunotherapy

2026-01-15

Abstract excerpt

Precise control of genome editing activity in vivo remains a major barrier to the clinical translation of CRISPR-based therapeutics, as current approaches cannot reliably restrict editing activity to target tissues 1,2,3 . Here we show that a magnetically gated baculoviral CRISPR platform enables spatial control of genome editing activity 4 . By coupling magnetic activation of viral transduction at target sites...

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Literature Corpus work: e1a65be0-75ad-558d-bd12-24c3ea68f53e
DOI: 10.64898/2026.01.14.699490

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