Article
Mitochondrial genetics of exceptional longevity in multigeneration matrilineages
2018-07-04
Abstract excerpt
Some heritable mitochondrial DNA (mtDNA) sequence variants may slow the rate of aging. The European mitochondrial haplogroup K has previously been reported to be increased in frequency in centenarians and nonagenarians relative to its frequency in younger individuals, by standard case/control study designs. To select for mitochondrial genomes likely to carry beneficial genetic variants, we screened a large genealo...
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Identifiers and source
- Literature Corpus work
- e116f57c-dcb9-57d2-8ef3-d172aeb959d6
- DOI
- 10.1101/361899