Article
Mitochondrial genetic variation in human bioenergetics, adaptation, and adult disease.
American journal of human biology : the official journal of the Human Biology Council - 1 Feb 2022
Friedrich Volney K, Rubel Meagan A, Schurr Theodore G
Abstract excerpt
OBJECTIVES: Mitochondria are critical for the survival of eukaryotic organisms due to their ability to produce cellular energy, which drives virtually all aspects of host biology. However, the effects of mitochondrial DNA (mtDNA) variation in relation to disease etiology and adaptation within contemporary global human populations remains incompletely understood. METHODS: To develop a more holistic understanding...
Topics
- Adaptation, Physiological
- DNA, Mitochondrial
- Energy Metabolism
- Genetic Variation
- Haplotypes
- Humans
- Mitochondria
