Mitochondrial DNA inherited variants are associated with successful aging and longevity in humans.

doi:10.1096/fasebj.13.12.1532

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Article

Mitochondrial DNA inherited variants are associated with successful aging and longevity in humans.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Sept 1999

De Benedictis G, Rose G, Carrieri G, De Luca M, Falcone E, Passarino G, Bonafe M, Monti D, Baggio G, Bertolini S, Mari D, Mattace R, Franceschi C

Abstract excerpt

Mitochondrial DNA (mtDNA) is characterized by high variability, maternal inheritance, and absence of recombination. Studies of human populations have revealed ancestral associated polymorphisms whose combination defines groups of mtDNA types (haplogroups) that are currently used to reconstruct human evolution lineages. We used such inherited mtDNA markers to compare mtDNA population pools between a sample of...

Topics

Adult
Aged
Aged, 80 and over
Aging
Biological Evolution
DNA, Mitochondrial
Female
Genetic Variation
Haplotypes
Humans
Italy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Longevity

Male

Middle Aged

Polymorphism, Genetic

Polymorphism, Restriction Fragment Length

Restriction Mapping

Sex Characteristics

Source

Open in PubMed

Identifiers

PMID: 10463944
DOI: 10.1096/fasebj.13.12.1532

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