Article
Mitochondrial haplogroup X is associated with successful aging in the Amish.
Human genetics - 1 Feb 2012
Courtenay Monique D, Gilbert John R, Jiang Lan, Cummings Anna C, Gallins Paul J, Caywood Laura, Reinhart-Mercer Lori, Fuzzell Denise, Knebusch Claire, Laux Renee, McCauley Jacob L, Jackson Charles E, Pericak-Vance Margaret A, Haines Jonathan L, Scott William K
Abstract excerpt
Avoiding disease, maintaining physical and cognitive function, and continued social engagement in long-lived individuals describe successful aging (SA). Mitochondrial lineages described by patterns of common genetic variants ("haplogroups") have been associated with increased longevity in different populations. We investigated the influence of mitochondrial haplogroups on SA in an Amish community sample....
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