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Mitochondrial Haplogroups

6 May 2008

Abstract excerpt

BACKGROUND: Rare mutations in the mitochondrial genome may cause disease. Mitochondrial haplogroups defined by common polymorphisms have been associated with risk of disease and longevity. We tested the hypothesis that common haplogroups predict risk of ischemic cardiovascular disease, morbidity from other causes, mortality, and longevity in a general population of European descent. METHODS AND RESULTS: We...

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PMID: 18458168
DOI: 10.1161/circulationaha.107.756809

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