Article

Progressive lengthening of 3′ untranslated regions of mRNAs by alternative cleavage and polyadenylation in cellular senescence of mouse embryonic fibroblasts

2015-11-11

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Cellular senescence has historically been viewed as an irreversible cell cycle arrest that acts to prevent cancer. Recent discoveries demonstrated that cellular senescence also played a vital role in normal embryonic development, tissue renewal and senescence-related diseases. Alternative cleavage and polyadenylation (APA) is an important layer of post-transcriptional regula...

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Literature Corpus work: e10136c6-ffd5-5680-8650-1780d8bdc54d
DOI: 10.1101/031302

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