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To polyadenylate or to deadenylate

15 Nov 2010

Abstract excerpt

mRNA polyadenylation and deadenylation are important processes that allow rapid regulation of gene expression in response to different cellular conditions. Almost all eukaryotic mRNA precursors undergo a co-transcriptional cleavage followed by polyadenylation at the 3' end. After the signals are selected, polyadenylation occurs to full extent, suggesting that this first round of polyadenylation is a default...

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PMID: 21084869
DOI: 10.4161/cc.9.22.13887

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