Article

Alternative polyadenylation mediated by CPSF5 regulates pro-inflammatory gene expression

2026-02-01

Abstract excerpt

The majority of mammalian genes contains more than one functional cleavage and polyadenylation site, so that selection of alternative sites leads to different 3’ ends of the mature transcripts. This mechanism can lead to the exclusion or retention of regulatory sequence elements, which affects post-transcriptional regulation of gene expression, such as RNA stability, localization or translation efficiency. We used...

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Literature Corpus work: 5df1102c-9173-5e99-b8d8-a2acf63ec190
DOI: 10.64898/2026.01.31.703030

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