Article

Further genetic diversification in multiple tumors and an evolutionary perspective on therapeutics

2015-08-25

Abstract excerpt

<h4>Abstracts</h4> The genetic diversity within a single tumor can be extremely large, possibly with mutations at all coding sites (Ling et al. 2015). In this study, we analyzed 12 cases of multiple hepatocellular carcinoma (HCC) tumors by sequencing and genotyping several samples from each case. In 10 cases, tumors are clonally related by a process of cell migration and colonization. They permit a detailed analy...

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Literature Corpus work: e06b7927-9bc1-5708-9306-6145443e024f
DOI: 10.1101/025429

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