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Modelling Acral Melanoma in Admixed Brazilians Uncovers Genomic Drivers and Targetable Pathways

2025-08-12

Abstract excerpt

<h4>ABSTRACT</h4> Acral melanoma (AM) is an aggressive melanoma subtype with limited therapeutic options and poor outcomes. In non-European descent and admixed populations, like those residing in Latin America, AM accounts for a significant proportion of cutaneous melanoma cases. Here, we performed comprehensive genomic and functional profiling of AM from a uniquely diverse Brazilian cohort. Whole-exome and trans...

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Literature Corpus work
e0671293-1dca-513c-9d1e-efb128c2ad76
DOI
10.1101/2025.08.08.25332963
Open publication

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Modelling Acral Melanoma in Admixed Brazilians Uncovers Genomic Drivers and Targetable PathwaysDOI 10.1101/2025.08.08.25332963
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