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Article

Targeted Genomic Profiling of Acral Melanoma

13 Jan 2019

Abstract excerpt

BACKGROUND: Acral melanoma is a rare type of melanoma that affects world populations irrespective of skin color and has worse survival than other cutaneous melanomas. It has relatively few single nucleotide mutations without the UV signature of cutaneous melanomas, but instead has a genetic landscape characterized by structural rearrangements and amplifications. BRAF mutations are less common than in other...

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PMID: 30657954
DOI: 10.1093/jnci/djz005

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