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Single-nucleus cross-tissue molecular reference maps to decipher disease gene function

2021-07-19

Abstract excerpt

Understanding the function of genes and their regulation in tissue homeostasis and disease requires knowing the cellular context in which genes are expressed in tissues across the body. Single cell genomics allows the generation of detailed cellular atlases in human tissues, but most efforts are focused on single tissue types. Here, we establish a framework for profiling multiple tissues across the human body at s...

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Identifiers and source

Literature Corpus work
e037465e-79cd-5f40-862e-8899a44adac5
DOI
10.1101/2021.07.19.452954
Open publication

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Single-nucleus cross-tissue molecular reference maps to decipher disease gene functionDOI 10.1101/2021.07.19.452954
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