Article

Human and rat skeletal muscle single-nuclei multi-omic integrative analyses nominate causal cell types, regulatory elements, and SNPs for complex traits

2020-07-02

Abstract excerpt

<h4>Background</h4> Skeletal muscle accounts for the largest proportion of human body mass, on average, and is a key tissue in complex diseases, mobility, and quality of life. It is composed of several different cell and muscle fiber types. <h4>Results</h4> Here, we optimize single-nucleus ATAC-seq (snATAC-seq) to map skeletal muscle cell-specific chromatin accessibility landscapes in frozen human and rat sample...

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Literature Corpus work: a9753e5a-6997-54e6-bcac-d185762c3cb3
DOI: 10.1101/2020.07.01.183004

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