Article

Continuous antiretroviral therapy induces progressive senescence-like reprogramming of alveolar macrophages

2025-04-04

Abstract excerpt

<h4>Background</h4> Advances in antiretroviral therapy (ART) have substantially improved the lives of people with HIV (PWH) and reduced HIV acquisition through pre-exposure prophylaxis (PrEP). However, the long-term effect of ART on the physiological state of cells remains poorly understood. Despite the success of ART in preventing the progression of HIV infection to AIDS, aging PWH are suffering from a dispropor...

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Literature Corpus work: e00ee080-f4e5-5c34-8df9-5f505442e5c4
DOI: 10.1101/2025.04.02.25325039

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