Back to search

Article

HIV-1 activates oxidative phosphorylation in infected CD4 T cells in a human tonsil explant model

2023-05-17

Abstract excerpt

<title>Abstract</title> <p> Human immunodeficiency virus type 1 (HIV-1) leads to a chronic, incurable infection that causes immune activation, resulting in chronic inflammation in people with HIV-1 (PWH) despite virologic suppression on antiretroviral therapy (ART). The mechanisms underlying this chronic inflammation are multifactorial; literature supports the role of lymphoid structures as reservoirs for viral...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
0923d985-e272-5379-930f-787a463b445b
DOI
10.21203/rs.3.rs-1910284/v5
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
HIV-1 activates oxidative phosphorylation in infected CD4 T cells in a human tonsil explant modelDOI 10.21203/rs.3.rs-1910284/v5
Multi-Omics Single-Cell Analysis Reveals Key Regulators of HIV-1 Persistence and Aberrant Host Immune Responses in Early InfectionSemantic proximity
Metabolome and transcriptome analysis of oral mucosa of HIV+ patients reveal a role for polyamine metabolic pathway in T cell dysfunctionSemantic proximity
A single-cell atlas reveals shared and distinct immune responses and metabolism during SARS-CoV-2 and HIV-1 infectionsSemantic proximity
Advances in Single‐Cell Sequencing for Infectious Diseases: Progress and PerspectivesSemantic proximity
STAT1-Mediated Regulation of IL-17A/CEBPB/NF-κB Axis in HIV-1 Infected Human Cerebral Organoids Reveals Therapeutic Targets for NeuroprotectionSemantic proximity
Genome-wide analysis of primary CD4+ and CD8+ T cell transcriptomes shows evidence for a network of enriched pathways associated with HIV diseaseSemantic proximity
Transcriptomic crosstalk between viral and host factors drives aberrant homeostasis of T-cell proliferation and cell death in HIV-infected immunological non-respondersSemantic proximity
Three immunoregulatory signatures define non-productive HIV infection in CD4 <sup>+</sup> T memory stem cellsSemantic proximity
Single-Cell Multi-Modal Differential Analysis of the Human Neo-Cortex in HIV Infection Reveals Similarities with Hallmarks of Alzheimer’s DiseaseSemantic proximity
Omic Technologies in HIV: Searching Transcriptional Signatures Involved in Long-Term Non-Progressor and HIV Controller Phenotypes.Semantic proximity
Spatially resolved single-cell atlas of the lung in fatal Covid19 in an African population reveals a distinct cellular signature and an interferon gamma dominated responseSemantic proximity
A Transcriptional Signature of Induced Neurons Differentiates Virologically Suppressed People Living With HIV from People Without HIVSemantic proximity
Select a neighboring publication to make it the new centre.