Article

Multi-Omics Single-Cell Analysis Reveals Key Regulators of HIV-1 Persistence and Aberrant Host Immune Responses in Early Infection

2024-11-05

Abstract excerpt

<h4>ABSTRACT</h4> The clearance of human immunodeficiency virus-1 (HIV-1) remains a significant public health challenge due to impaired cellular immune responses and HIV-1 maintenance during acute infection. However, the genetic and epigenetic changes influencing the immune response on host infected cells remain unclear. Here, this study analyzes HIV-1 infected CD4+ T cells from peripheral blood mononuclear cells...

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Literature Corpus work: e46bc031-19a1-5999-8f14-d21d7dbc6e04
DOI: 10.1101/2024.11.04.621999

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