Article
Chromatin is frequently unknotted at the megabase scale
2019-09-09
Abstract excerpt
Knots in the human genome would greatly impact diverse cellular processes ranging from transcription to gene regulation. To date, it has not been possible to directly examine the genome in vivo for the presence of knots. Recently, methods for serial fluorescent in situ hybridization have made it possible to measure the 3d position of dozens of consecutive genomic loci, in vivo. However, the determination of whet...
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Identifiers and source
- Literature Corpus work
- dfb4a1c7-ef06-5e1e-b805-a45b7665b864
- DOI
- 10.1101/762872