Article

GPSeq reveals the radial organization of chromatin in the cell nucleus

2020-05-26

Abstract excerpt

<title>Abstract</title> <p>With the exception of lamina-associated domains, the radial organization of chromatin in mammalian cells remains largely unexplored. Here, we describe genomic loci positioning by sequencing (GPSeq), a genome-wide method for inferring distances to the nuclear lamina all along the nuclear radius that works by gradual enzymatic restriction of chromatin from the nuclear lamina towards the n...

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Literature Corpus work: 6580481e-4447-587d-a592-9b9170dcade5
DOI: 10.21203/rs.3.pex-570/v1

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