Article

Genome-wide mapping of persistent long-range correlation in the complete telomere-to-telomere human reference genome

2026-07-19

Abstract excerpt

Long-range correlations (LRCs) in DNA sequences have been reported for decades, but their interpretation has been limited by incomplete representation of repetitive and structurally complex regions in earlier human genome assemblies. Here, we use the complete telomere-to-telomere (T2T) human reference genome to systematically map LRC structure across all human chromosomes. Most chromosomes exhibited persistent lon...

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Literature Corpus work: def7077f-a051-5c67-94c1-fb83c9c8b05d
DOI: 10.64898/2026.07.19.739401

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