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Comprehensive landscape of potential CTCF-binding sites across the complete telomere-to-telomere human genome

2026-07-21

Abstract excerpt

CCCTC-binding factor (CTCF) is a master regulator of the human genome, directly modulating both transcription and 3D genome organization. However, previous human genome-wide maps of its binding sites have been built on an incomplete assembly, leaving out many repetitive, difficult-to-sequence regions. Here, we leverage the telomere-to-telomere human assembly to generate a complete catalog of potential CTCF-binding...

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Literature Corpus work
0de5d1a1-4144-591a-a3eb-3023a959045a
DOI
10.64898/2026.07.18.739380
Open publication

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Comprehensive landscape of potential CTCF-binding sites across the complete telomere-to-telomere human genomeDOI 10.64898/2026.07.18.739380
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