Article

Complete guide RNA design for CRISPR-mediated regulation of human long noncoding RNA transcription

2018-03-28

Abstract excerpt

Transcription inhibition and activation of long noncoding RNAs (lncRNAs) mediated by clustered regularly interspaced short palindromic repeat (CRISPR)/Cas9 technology provides potential advantages in high-throughput functional genomics studies over RNA interference or overexpression platforms. In this work, we identify over 90,000 lncRNA transcription start sites (TSSs) based on the MiTranscriptome human genome an...

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Literature Corpus work: def33dd3-1570-5fcb-a1f6-9d20c46087a9
DOI: 10.1101/290338

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