Article

mtgRNA-db: An annotated database of multi-target CRISPR-Cas9 guide-RNAs in the human genome

2025-05-10

Abstract excerpt

CRISPR-Cas9 guide-RNA design tools can be used to identify guide-RNAs that target single human genomic loci. However, these approaches limit their effect to a single locus. Here, we generate a database of potential individual guide-RNAs that target multiple sites in the genome at once. All guide-RNAs in this database are curated with on- and off-target quantification and enrichment scores for genomic elements such...

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Literature Corpus work: 2f4da455-ae8c-5b77-8222-8c7893206d53
DOI: 10.1101/2025.05.07.652656

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