Article
Smc6 And Top1 Prevent Aberrant Recombination At The Silent Mating-Type Locus HMR In Budding Yeast
2017-05-04
Abstract excerpt
The structural maintenance of chromosomes 5/6 (Smc5/6) complex controls recombination in response to replicative stress, within the ribosomal DNA, and at telomeres. It has also been suggested to act in parallel with topoisomerase 1 (Top1) in the resolution of replication-induced superhelical stress under unperturbed conditions. In addition to this, human Smc5/6 was recently shown to suppress the expression of gene...
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Identifiers and source
- Literature Corpus work
- dec478a8-247e-50aa-8aa7-8183bde06b6d
- DOI
- 10.1101/134171