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Article

A novel function of the DNA repair gene rhp6 in mating-type silencing by chromatin remodeling in fission yeast.

Molecular and cellular biology - 1 Sept 1998

Singh J, Goel V, Klar A J

Abstract excerpt

Recent studies have indicated that the DNA replication machinery is coupled to silencing of mating-type loci in the budding yeast Saccharomyces cerevisiae, and a similar silencing mechanism may operate in the distantly related yeast Schizosaccharomyces pombe. Regarding gene regulation, an important function of DNA replication may be in coupling of faithful chromatin assembly to reestablishment of the parental...

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Identifiers

PMID: 9710635
DOI: 10.1128/MCB.18.9.5511
PMCID: PMC109136

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Related research

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Research trail→

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A novel function of the DNA repair gene rhp6 in mating-type silencing by chromatin remodeling in fission yeast.PMID 9710635Read ↗

Identification of Uhp1, a ubiquitinated histone-like protein, as a target/mediator of Rhp6 in mating-type silencing in fission yeast.Semantic proximity Read ↗

Chromodomain protein Swi6-mediated role of DNA polymerase alpha in establishment of silencing in fission Yeast.Semantic proximity Read ↗

Smc6 And Top1 Prevent Aberrant Recombination At The Silent Mating-Type Locus HMR In Budding YeastSemantic proximity Read ↗

Smc5/6 maintains stalled replication forks in a recombination-competent conformation.Semantic proximity Read ↗

A novel type of silencing factor, Clr2, is necessary for transcriptional silencing at various chromosomal locations in the fission yeast Schizosaccharomyces pombe.Semantic proximity Read ↗

Msc1 links dynamic Swi6/HP1 binding to cell fate determination.Semantic proximity Read ↗

New insights into donor directionality of mating-type switching in Schizosaccharomyces pombe.Semantic proximity Read ↗

Establishment and maintenance of a heterochromatin domain.Semantic proximity Read ↗

PCNA connects DNA replication to epigenetic inheritance in yeast.Semantic proximity Read ↗

The rhp6+ gene of Schizosaccharomyces pombe: a structural and functional homolog of the RAD6 gene from the distantly related yeast Saccharomyces cerevisiae.Semantic proximity Read ↗

Mutations in deoxyribonucleotide biosynthesis pathway cause spreading of silencing across heterochromatic barriers at the mating-type region of the fission yeast.Semantic proximity Read ↗

The role of novel genes rrp1(+) and rrp2(+) in the repair of DNA damage in Schizosaccharomyces pombe.Semantic proximity Read ↗

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