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Article

Structural analyses of Sum1-1p-dependent transcriptionally silent chromatin in Saccharomyces cerevisiae.

Journal of molecular biology - 10 Mar 2006

Yu Qun, Elizondo Susan, Bi Xin

Abstract excerpt

In Saccharomyces cerevisiae, transcriptional silencing of the cryptic mating loci HML and HMR is established by the combined actions of cis-acting silencers and trans-acting proteins, including Sir2p, Sir3p and Sir4p. The Sir proteins serve as an integral part of a special silent chromatin at the HM loci. Deletion of any of the SIR2-SIR4 genes leads to a complete loss of silencing. However, the SUM1-1 mutation...

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Source

Identifiers

PMID: 16406069
DOI: 10.1016/j.jmb.2005.11.089

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Structural analyses of Sum1-1p-dependent transcriptionally silent chromatin in Saccharomyces cerevisiae.PMID 16406069Read ↗

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Elaboration, diversification and regulation of the Sir1 family of silencing proteins in Saccharomyces.Semantic proximity Read ↗

A novel allele of SIR2 reveals a heritable intermediate state of gene silencing.Semantic proximity Read ↗

Smc6 And Top1 Prevent Aberrant Recombination At The Silent Mating-Type Locus HMR In Budding YeastSemantic proximity Read ↗

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