Article

Dynamic chromatin organization and regulatory interactions in human endothelial cell differentiation

2022-04-16

Abstract excerpt

<h4>Background</h4> Vascular endothelial cells are a mesoderm-derived lineage with many essential functions, including angiogenesis and coagulation. However, the gene regulatory mechanisms that underpin endothelial specialization are largely unknown, as are the roles of 3D chromatin organization in regulating endothelial cell transcription. <h4>Methods</h4> To investigate the relationships between 3D chromatin o...

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Literature Corpus work: dead8787-4bf6-5b96-98e7-8e9e5306ca09
DOI: 10.1101/2022.04.15.488491

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