Article

Human HLF <sup>neg</sup> placental erythro-myeloid progenitors give rise to HLA Class II <sup>neg</sup> Hofbauer cells

2022-02-27

Abstract excerpt

The earliest macrophages are generated during embryonic development from erythro-myeloid progenitors (EMPs) via primitive haematopoiesis. This process is still poorly understood in humans but is generally thought to be spatially restricted to the yolk sac. Human fetal placental macrophages, Hofbauer cells (HBC), arise during the primitive haematopoietic wave, yet are unlikely to be yolk sac derived as they appear...

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Literature Corpus work: de9966d8-8a1a-5f43-a152-7a82e49a2f55
DOI: 10.1101/2022.02.26.482080

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