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The Ontogeny and Function of Placental Macrophages

21 Oct 2021

Abstract excerpt

The placenta is a fetal-derived organ whose function is crucial for both maternal and fetal health. The human placenta contains a population of fetal macrophages termed Hofbauer cells. These macrophages play diverse roles, aiding in placental development, function and defence. The outer layer of the human placenta is formed by syncytiotrophoblast cells, that fuse to form the syncytium. Adhered to the syncytium at...

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PMID: 34745147
DOI: 10.3389/fimmu.2021.771054

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