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Erythro-myeloid progenitor origin of Hofbauer cells in the early mouse placenta

15 Apr 2022

Abstract excerpt

Hofbauer cells (HBCs) are tissue macrophages of the placenta thought to be important for fetoplacental vascular development and innate immune protection. The developmental origins of HBCs remain unresolved and could implicate functional diversity of HBCs in placenta development and disease. In this study, we used flow cytometry and paternally inherited reporters to phenotype placenta macrophages and to identify...

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PMID: 35438172
DOI: 10.1242/dev.200104

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